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Figure 1 | Kinetoplastid Biology and Disease

Figure 1

From: In silico, biologically-inspired modelling of genomic variation generation in surface proteins of Trypanosoma cruzi

Figure 1

Multiple-point mutation model. A (reference) input DNA sequence, gi,0, encodes an amino acid sequence, Agi,0, at generation '0'. Random selection and mutation of nucleotides generate a new sequence, gi,1, at generation '1', which encodes a mutated amino acid sequence, Agi,1. The variability of a gene i, gi,j, at generation j, is estimated by measuring the difference between Agi,0and Agi,j.

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Kinetoplastid Biology and Disease

ISSN: 1475-9292