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Figure 11 | Kinetoplastid Biology and Disease

Figure 11

From: Consultative meeting to develop a strategy for treatment of cutaneous leishmaniasis. Institute Pasteur, Paris. 13–15 June, 2006

Figure 11

Immuno-chemotherapy of CL caused by L. braziliensis in Brazil. Double-blind controlled trial of Mayrink's vaccine (killed L. amazonensis) plus low dose (8 mg/Kg/d) Sb+5 vs. low dose Sb+5. Patients received daily injections of the combination or drug alone for 10 days followed by 10-day rest (one cycle). All patients (47/47) were cured in the combination group after 4 cycles (80 days) vs. 4/47 in the chemotherapy alone group. The non-responders were rescued with full dose antimony. (Adopted from Machado-Pinto et al. Int. J. Dermat. 2002; 41:73-8.)

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Kinetoplastid Biology and Disease

ISSN: 1475-9292