Leishmaniaamastigotes as targets for drug screening

Table 1 Leishmania expressing reporter gene whose capacity to be used in vitro for drug screening procedure has been determined

Species	Reporter gene	Expression	Ref
L. donovani/L. donovaniR	Firefly luciferase	Episomal	16
L. amazonensis	Firefly luciferase	Integration	17
L. infantum/L. infantum RSbIII¹	Firefly luciferase	Episomal	14
L. donovani	GFP	Episomal	7
L. donovani R ²			10
L. amazonensis	β-Lactamase	Episomal	12
L. major

¹ in vitro selected trivalent antimony resistant L. infantum. ² Field isolates of L. donovani resistant to pentavalent antimony.