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Figure 2 | Kinetoplastid Biology and Disease

Figure 2

From: Role of the long slender to short stumpy transition in the life cycle of the african trypanosomes

Figure 2

Resistant B10BR mice infected with pleomorphic Trypanosoma brucei rhodesiense Legend: B10BR mice infected with the pleomorphic Loutat-1 clone of Trypanosoma brucei rhodesiense. Panel A shows the number of trypanosomes per ml of blood. Panel B shown the percentage of these trypanosomes that are in the LS stage; at 216 hours, nearly all of the remaining parasites are the SS form. Panel C depicts the percentage of mouse hourly carbohydrate intake (Haugh D, Technical Director Laboratory Group, Purina Mills, St. Louis Missouri, (Personal Communication, 2002) that would be consumed by the circulating trypanosomes. Von Brand [18] estimated that trypanosomes use 50–100% of their dry weight in glucose each hour. For these calculations, LS trypanosomes were estimated to use 75% of their dry weight and the SS form to use half as much, or 37.5%.

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