Table 1 Support for monophyly of the genus Trypanosoma in protein phylogenies constructed by three different methods.
Family | Aligned sites | Trypanosoma species 1 | ME 2 | MP | QML |
|---|---|---|---|---|---|
Actin | 375 | Tb, Tcr | yes (A,71) 3 | yes (A,71) | yes (A,100) |
Adenylate cyclase | 1142 | Tb,Tcr | yes (A, 63) | yes (A, 94) | no |
ATPase, subunit 6 | 225 | Tb,Tcr | no (B,37) | yes (A, 92) | no |
α tubulin | 451 | Tb,Tcr | yes (A,99) | yes (A,99) | yes (A,100) |
β tubulin | 442 | Tb,Tcr | yes (A,98) | yes (A,96) | yes (A,100) |
Calreticulin | 393 | Tco,Tcr | yes (A,95) | yes (A,97) | yes (A,100) |
Cdc2-related kinase 3 | 290 | Tb,Tcr | yes (A,97) | yes (A,68) | yes (A,99) |
CDKRS | 73 | Tb,Tcr | yes (A,96) | yes (A,72) | yes (A,100) |
CRK1 | 289 | Tb,Tco,Tcr | yes (A,100) | yes (A,99) | yes (A,98) |
Cyclophilin A | 164 | Tb,Tco,Tcr, Tvi | no (B,34) | no (B,49) | no |
Cysteine proteinase | 223 | Tb,Tco,Tcr,Tr | yes (A,98) | yes (A,98) | yes (A,98) |
Cytochrome b | 171 | Tb,Tcr | no | no (B,60) | no |
Cytochrome-c oxidase II | 198 | Tb,Tcr | no (B,66) | no (B,35) | no (B,87) |
DHFR-TS | 455 | Tb,Tcr,Tve | no (B,49) | no (B,65) | yes (A,100) |
DNA-directed RNA polymerase II, large subunit | 1599 | Tb,Tcr | yes (A,99) | yes (A,100) | yes (A,100) |
DNA topoisomerease II | 1171 | Tb,Tcr | yes (A,100) | yes (A,100) | yes (A,100) |
EFH5 | 147 | Tb,Tcr | yes (A,78) | yes (A,67) | no |
EF-1a | 444 | Tb,Tcr | yes (A,99) | yes (A,93) | yes (A,100) |
GAPDH | 337 | Tb,Tcr,Tev, Tr,Tvi | yes (A,98) | yes (A,94) | yes (A,100) |
Glucose-6-phosphate isomerase | 550 | Tb,Tcr | yes (A,97) | yes (A,70) | yes (A,100) |
GRP78 | 624 | Tb,Tco,Tcr | yes (A,98) | yes (A,97) | yes (A,100) |
HEXBP | 161 | Teq,Tcr | yes (A,100) | yes (A,100) | yes (A,100) |
HGPRT | 177 | Tb,Tcr | yes (A,96) | yes (A,60) | yes (A,94) |
HSP60 | 557 | Tb,Tcr | yes (A,85) | yes (A,96) | yes (A,100) |
HSP70 | 511 | Tb,Tcr | yes (A,79) | yes (A,50) | yes (A,100) |
HSP90 | 613 | Tb,Tcr | yes (A,99) | yes (A,100) | yes (A,100) |
Malate dehydrogenase | 310 | Tb,Tcr | yes (A,64) | yes (A,57) | no |
MDR-A | 877 | Tb,Tcr | yes (A,99) | yes (A,100) | yes (A,100) |
MDR-E | 877 | Tb,Tcr | yes (A,100) | yes (A,100) | yes (A,100) |
Oligopeptidase B | 667 | Tb,Tcr | yes (A,99) | yes (A,100) | yes (A,100) |
PAR-2 | 328 | Tb,Tcr | yes (A,81) | yes (A,81) | no (B,87) |
PAR-3 | 328 | Tb,Tcr | yes (A,58) | yes (A,66) | yes (A,51) |
Periredoxin | 188 | Tb,Tcr | yes (A,90) | yes (A,51) | yes (A,99) |
Proteasome subunit α-5 | 237 | Tb,Tcr | yes (A100) | yes (A,99) | yes (A,100) |
Protein kinase A reg. subunit | 372 | Tb,Tcr | yes (A,97) | yes (A,99) | yes (A,100) |
Pteridine reductase | 238 | Tb,Tcr | yes (A,94) | yes (A,55) | yes (A,100) |
P-type H+-ATPase | 832 | Tb,Tcr | yes (A,76) | no (B,53) | no (B,91) |
Ribosomal protein P0 | 312 | Tb,Tcr | yes (A,97) | yes (A,97) | yes (A,100) |
S-adenosyl methionine decarboxylase | 324 | Tb,Tcr | yes (A,63) | no (B,68) | yes (A,72) |
THT | 432 | Tb,Tco,Tcr, Tvi | no (B,94) | no (B,86) | no (B,96) |
TPIS | 247 | Tb,Tcr | yes (A,98) | yes (A,95) | yes (A,92) |
Trypanothione reductase | 407 | Tb, Tco, Tcr, Tve | yes (A,100) | no (B,100) | yes (A,100) |